Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Sigma Aldrich Fine Chemicals Biosciences Formic acid >=95%, FCC, FG | 64-18-6 | MFCD00003297 | 1KG
Formic acid >=95%, FCC, FG | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1KG
Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 10 MM * 1 ML
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It is intended for research use only and available in various forms, including solid and as a 10 mM * 1 mL solution in DMSO.
- Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
- Intended for research use only
- Purity of 99.91%
- Molecular weight of 403.56
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL (247.79 mM)
- Induces a dose-dependent decrease in circulating lymphocytes in vivo
- Achieves a maximum concentration of 4 μM in rats at 2 hours post-dose with a half-life of 8 hours
- Related to respiratory, inflammatory, and pulmonary diseases, and lung fibrosis
- Affects inflammation/immunology, GPCR/G protein, and LPL receptor signaling pathways
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, 88-91, 64-18-6, MFCD00003297
Formic acid ACS reagent, 88-91
Sigma Aldrich Fine Chemicals Biosciences Formic acid | 64-18-6 | MFCD00003297 | 500 mL
Formic acid | Purity: 96% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 500 mL
Medchemexpress LLC SLB1122168 formic | 2999629-17-1 | C23H37N3O3 | 50 MG
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It leads to a dose-dependent decrease in circulating lymphocytes, and in rats, it achieves a maximum concentration of 4 μM at 2 hours post-dose, maintaining levels ≥1 μM for 24 hours with a half-life of 8 hours.
- Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
- Induces a dose-dependent decrease in circulating lymphocytes
- Relevant for research in respiratory disease, inflammation or immune system disease, pulmonary disease, and lung fibrosis
- Acts on inflammation/immunology signaling pathways, GPCR/G protein, and LPL receptor
Medchemexpress LLC LCC-12 (formic) | 3029253-76-4 | 99.9% | 460.57 | 5 MG
LCC-12 formic is a dimer of metformin that targets mitochondrial copper(II), leading to a decrease in the NAD(H) pool and modulation of inflammatory responses. It reduces inflammation in mouse models of bacterial and viral infections and serves as a tool for investigating metabolic diseases through its effects on cell plasticity and epigenetic programming.
- Targets mitochondrial copper(II).
- Decreases the NAD(H) pool.
- Modulates inflammatory responses.
- Reduces inflammation in mouse models of bacterial and viral infections.
- Serves as a tool for investigating metabolic diseases.
- Affects cell plasticity.
- Affects epigenetic programming.
Sigma Aldrich Fine Chemicals Biosciences Formic acid, 64-18-6, MFCD00003297, 500 mL
Linear Formula: HCOOH, Molecular Weight: 46.03, puriss., meets analytical specifications of DAC, FCC, 98.0-100%.
Medchemexpress LLC Ammonium formate | 540-69-2 | MFCD00013103 | 98.5% | 63.06 g/mol | CH5NO2 | 50g
Formic acid ammonium salt is an endogenous metabolite
IMEB, Inc Tek-Select Formic Acid Plus, 32 oz Bottle, This Formula is a Fixative and Decalcifier, Fresh Tissue can be Placed Directly into Formic Acid Plus to Fix and Decalcify Simultaneously
Tek-Select Formic Acid Plus, 32 oz Bottle. This formula is a fixative and decalcifier. Fresh tissue can be placed directly into Formic Acid Plus to fix and decalcify simultaneously.
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemicals | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 25g | 480143861
Formic Acid, ACS Grade | Oakwood Chemicals | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 25g | 480143861